Anabolic steroid. Nandrolone Phenylpropionate is a white to off-white crystalline powder with a characteristic odor. Practically insoluble in water, sparingly soluble in ethanol, freely soluble in chloroform and acetone. Nandrolone decanoate: white to yellow crystals. Practically insoluble in water, freely soluble in ethanol, ether, acetone, chloroform, oils.

Pharmacological effect
Pharmacological action – anabolic, androgenic, antianemic, antitumor.
Pharmacology
It binds to specific receptor proteins on the surface of cells of target organs, forms a receptor-nandrolone complex, which provides transport of the latter across the cell membrane into the hyaloplasm, from where it diffuses through the membrane nuclear to the cell nucleus and causes the activation of regulatory genes. Androgenic properties include stimulation of nucleic acid (DNA, RNA), structural protein synthesis, increased tissue respiration and oxidative phosphorylation in skeletal muscle with accumulation of macroergs (ATP, creatine phosphate) ; increases muscle mass and reduces the amount of fatty tissue.
Accelerates the growth of male genitalia and the formation of secondary sex characteristics according to the male type. It promotes the calcification of growth areas in the bones and the arrest of skeletal growth. Stimulates the secretory activity of androgen-dependent glands: male genital (activation of the spermatogenesis process), sebaceous; in high doses, it suppresses Leydig cells and reduces the synthesis of endogenous sex hormones by inhibiting the production of FSH and LH by the pituitary gland (negative feedback). The anabolic effect is manifested in the activation of repair processes in the epithelium (tegumentary and glandular), bone and muscle tissues as a result of stimulation of protein synthesis and structural components of cells.
Increases the integrity of amino acid absorption from the small intestine (as part of a high protein diet), creating a positive nitrogen balance. It stimulates the production of erythropoietin and activates anabolic processes in the bone marrow, which, with the simultaneous administration of iron preparations, is manifested by an antianemic effect. Violates the synthesis of vitamin K-dependent plasma coagulation factors (II, VII, IX, X) in the liver, changes the plasma lipid profile (increases the concentration of LDL and reduces the content of HDL), improves the reabsorption of sodium and water in the kidneys, contributing to the formation of peripheral edema.
After administration / m of 100 mg Cmax is created in 1-3 weeks. It undergoes biotransformation in the liver with the formation of 17-ketosteroids. It is excreted mainly with urine (more than 90%) and about 6% with faeces.
Diabetic retinopathy; progressive muscular dystrophy; Werdnig-Hoffmann syndrome; conditions characterized by a negative Ca2+ balance (senile and post-menopausal osteoporosis, prolonged corticosteroid therapy); an increase in catabolic processes that deplete the body’s resources (chronic infectious diseases, serious injuries, extensive surgical interventions, steroid myopathy); anemia in chronic renal failure, myelofibrosis, myelosclerosis, myeloid bone marrow aplasia (refractory to conventional treatment), bone marrow damage due to metastasis of malignant neoplasms, myelotoxic drugs and metal salts heavy; inoperable (metastatic) breast carcinoma in postmenopausal women or after oophorectomy; growth retardation in children caused by growth hormone deficiency.

Nandrolone Side Effects
In men and women: progression of atherosclerosis (increased LDL concentration and decreased HDL concentration), iron deficiency anemia, peripheral oedema, dyspeptic disorders (abdominal and epigastric pain, nausea, vomiting), liver disorders insufficiency with jaundice, leukemia-like syndrome (changes in the number of white blood cells, pain in the long bones), hypocoagulation with bleeding tendency, hepatonecrosis (dark stools, vomiting blood, headache, malaise, respiratory failure), hepatocellular carcinoma , hepatic purpura (dark urine, discoloration of stools, urticaria, spot or macular haemorrhagic eruptions on the skin and mucous membranes, pharyngitis or tonsillitis), cholestatic hepatitis (yellow discoloration of the sclera and skin, pain in the right upper quadrant, dark urine, discolored stools).
In women, virilism (enlargement of the clitoris, hoarse voice, dys- and amenorrhea, male-type hairiness), hypercalcemia (CNS depression, nausea, vomiting, fatigue).
In men:
- in the prepubertal period: virilism (acne, penis enlargement, priapism, formation of secondary sexual characteristics), idiopathic hyperpigmentation of the skin, growth retardation or arrest (calcification of the epiphyseal growth zones of the tubular bones);
- in the postpubertal period – irritation of the bladder (increased frequency of impulses), compaction of the mammary glands, gynecomastia, priapism, in old age – hypertrophy and / or carcinoma of the prostate.